Research

Research Interests:

My research interests include biomedical signal processing, wearable device design, physiological monitoring systems, acoustic analysis, digital biomarkers, artificial intelligence for healthcare, applied machine learning and data science.

To meet the compelling need for quantitative schemes for assessing disease or injury state, my research: (i) proposes wearable sensor modalities to enable continuous and non-invasive health and treatment monitoring regardless of time and environmental settings, (ii) develops algorithms to extract clinically useful information from the acoustical and vibrational signals captured through these sensors, and (iii) uses this information to derive digital biomarkers for quantifying human health.


Journal Publications:

  1. G. C. Ozmen, M. Safaei, B. Semiz, D. C. Whittingslow, J. L. Hunnicutt, R. Hash, J. W. Xerogeanes, O. T. Inan, “Detection of Meniscal Tear Effects on Tibial Vibration Using Passive Knee Sound Measurements”IEEE Transactions on Biomedical Engineering (TBME), In Press.
  2. B. Semiz, A. M. Carek, J. C. Johnson, S. Ahmad, A. Heller, F. G. Vicente, S. Caron, C. W. Hogue, M. Etemadi, and O. T. Inan, “Non-Invasive Wearable Patch Utilizing Seismocardiography for Peri-Operative Use in Surgical Patients”IEEE Journal of Biomedical and Health Informatics (JBHI), In Press. [paper]
  3. B. Semiz, S. Hersek, M. B. Pouyan, C. Partida, L.B. Arroyo, V. Selby, G. Wieselthaler, J. Rehg, L. Klein and O.T. Inan, “Detecting Suspected Pump Thrombosis in Left Ventricular Assist Devices via Acoustic Analysis”, IEEE Journal of Biomedical and Health Informatics (JBHI), v. 24, no. 7, pp. 1899-1906, 2020. Selected as the featured article in the Special Issue on Integrative Sensor Networks, Informatics and Modeling for Precision and Preventative Medicine. [paper]
  4. S. Hersek, B. Semiz, M.M.H. Shandhi, L. Orlandic, and O.T. Inan, “A Globalized Model for Mapping Wearable Seismocardiogram Signals to Whole-Body Ballistocardiogram Signals Based on Deep Learning”IEEE Journal of Biomedical and Health Informatics (JBHI), v. 24, no. 5, pp. 1296-1309, 2020.
  5. J. Zia,  J. Kimball,  S. Hersek, M.M.H. Shandhi, B. Semiz, and O.T. Inan, “A Unified Framework for Quality Indexing and Classification of Seismocardiogram Signals”, IEEE Journal of Biomedical and Health Informatics (JBHI), v. 24, no. 4, pp. 1080-1092, 2020. [paper]
  6. M.M.H. Shandhi, B. Semiz, S. Hersek, N. Goller, F. Ayazi, and O.T. Inan, “Performance Analysis of Gyroscope and Accelerometer Sensors for Seismocardiography-Based Wearable Pre-Ejection Period Estimation”IEEE Journal of Biomedical and Health Informatics (JBHI), v. 23, no. 6, pp. 2365-2374, 2019. [paper]
  7. B. Semiz, S. Hersek, D. Whittingslow, L. Ponder, S. Prahalad, and O. T. Inan, “Using Knee Acoustical Emissions for Sensing Joint Health in Patients with Juvenile Idiopathic Arthritis: A Pilot Study”, IEEE Sensors Journal, v. 18, no. 22, pp. 9128-9136, 2018. [paper]

Conference Publications:

  1. B.Semiz, M.E. Gursoy, M.M.H. Shandhi, L. Orlandic, V. Mooney, O.T. Inan, “Automatic Subject Identification Using Scale-Based Ballistocardiogram Signals”, EAI MobiHealth 2021, Virtual.
  2. B. Semiz, M.M.H. Shandhi, J. Fan, S. Dowling, L. Klein, and O.T. Inan, “Quantification of Hemodynamic Responses to Diuretic Changes in Patients with Heart Failure using Ballistocardiogram and Electrocardiogram Recordings”, IEEE Biomedical and Health Informatics Conference (BHI), Chicago, IL, 2019. [paper] [poster]
  3. B. Semiz, S. Hersek, D. Whittingslow, L. Ponder, S. Prahalad, and O.T. Inan, “Change Point Detection in Knee Acoustic Emissions using the Teager Operator: A Preliminary Study in Patients with Juvenile Idiopathic Arthritis”IEEE Biomedical and Health Informatics Conference (BHI), Chicago, IL, 2019. [paper][poster]
  4. B. Semiz, S. Hersek, C. Partida, L.B. Arroyo, V. Selby, G. Wieselthaler, O.T. Inan, and L. Klein, “Blood-Biomarker-Based Acoustical Feature Selection Improves Overall Classification Accuracy for Pump Thrombosis in Left Ventricular Assist Devices”, American College of Cardiology Annual Scientific Session, New Orleans, LA, 2019. [poster]
  5. B. Semiz, S. Hersek, M. Baran Pouyan, C. Partida, O. T. Inan, and L. Klein, “Use of Ventricular Assist Device Acoustical Signatures to Detect Device Thrombosis”, Heart Failure Society of America Meeting, Nashville, TN, 2018. (Selected for presentation in the Moderated Poster Session, 3.8% of all accepted papers.) [poster]
  6. D. Whittingslow, B. Semiz, L. Ponder, P.V. Fernandez, O.T. Inan, S. Prahalad, “Knee Joint Sounds: A Non-Invasive Modality for Classifying Knee Joint Health in Juvenile Idiopathic Arthritis”, American College of Rheumatology Annual Meeting, San Diego, CA, 2017.
  7. D. Whittingslow, B. Semiz, L. Ponder, A. Wiens, O.T. Inan, S. Prahalad, “Analysis and Implications of Non-Invasive Knee Acoustical Emissions in Juvenile Idiopathic Arthritis”American College of Rheumatology Pediatric Rheumatology Symposium, Houston, TX, 2017. [poster]

Dissertation:

  • B. Semiz, Digital Biomarker Discovery for Non-Invasive Health Monitoring with Acoustic and Vibration Signals”, Ph.D. Dissertation, Georgia Institute of Technology, 2020.

Projects with Media Coverage:

  • CNN: “This is what your knee sounds like: “Chhh, chhh, chhh”, Nov 2, 2017.
  • GT Research Horizons: “Mending a Broken Heart”, Feb 14, 2019.
  • Fox 5 Atlanta: “Georgia Tech researchers say knee sounds reveal secrets about joint health”, Sep 16, 2019.
  • Fox 5 Atlanta: “Georgia Tech researchers develop patch to track heart failure”, Sep 18, 2019.