Publications from independent laboratory


Batman, U., Deretic, J.  Firat-Karalar, E.N (2022) The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization. PLOS Biology in press


Tiryaki, F., Deretic, J.  Firat-Karalar, E.N (2022) ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium content regulation. FEBS Journal


Arslanhan, M.D., Rauniyar, N. , Yates, J.R., Firat-Karalar, E.N (2020) Aurora Kinase A proximity interactome reveals centriolar satellites as regulators of its function during primary cilium biogenesis. EMBO Reports

Biorxiv link:

Firat-Karalar, E.N (2022) A Tour de Force of Primary Cilium Biogenesis. Nature Reviews Molecular Cell Biology


Conkar, D., Firat-Karalar, E.N (2020) Microtubule-associated proteins and emerging links to primary cilium structure assembly, maintenance and disassembly. FEBS Journal 15423


Odabasi, E., Batman, U., Firat-Karalar, E.N Unraveling the mysteries of centriolar satellites: time to rewrite the textbooks about the centrosome/cilium complex (2020) Mol Biol Cell Apr 15;31(9):866-872


Aydin, O.Z., Taflan, S.O. , Gurkaslar, C.,  Firat-Karalar, E.N  Acute inhibition of centriolar satellite function and positioning reveals their functions at the primary cilium (2020) PLOS Biology


Zirhlioglu, H., Culfa, E., Arslanhan, M.D., Firat-Karalar, E.N. CCDC57 Cooperates with Microtubules and Microcephaly Protein Cep63 and Regulates Centriole Duplication and Mitotic Progression (2020) Cell Reports 


Arslanhan, M.D., Gulensoy, D., Firat-Karalar, E.N (2020) A proximity mapping journey into the biology of the mammalian centrosome/cilium complex. Cells. Jun 3;9(6):E1390.


Firat-Karalar, E.N. (2020), Proximity mapping of the microtubule plus-end tracking protein SLAIN2 using the BioID approach. Turk J Biol. Apr2;44(2):61-72


Sadeghi, S., Melikov, R. Conkar, D., Firat-Karalar, E.N., Nizamoglu, S. (2020). Ultra-Efficient and High-Quality white light-emitting devices using fluorescent proteins in aqueous medium. Advanced Materials Technologies. May 4, 2000061


Muratcioglu, S., Aydin, C., Odabasi, E., Ozdemir, S., Firat-Karalar, E.N., Jang, H., Tsai, C.J., Nussinov, R., Kavakli, I.H., Gursoy, A., Keskin, O (2020). Oncogenic KRas4B dimerization influences Erk and Akt phosphorylation. Journal of Molecular Biology, Feb 14;432(4):1199-1215


Conkar, D., Bayraktar, H., Firat-Karalar, E.N (2019) Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors. Scientific Reports. Oct 3:9(1):14250


Odabasi, E., Gul,S., Kavakli, IH., Firat-Karalar, E.N Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation (2019). EMBO Reports. Jun;20(6). pii: e47723

*published in biorxiv (


Sadeghi, S., Melikov, R. Jalali, HB., Karatum, O., Srivastava, SB., Conkar, D., Firat-Karalar, E.N., Nizamoglu, S. . Ecofriendly and efficient luminescent solar concentrators based on fluorescent proteins (2019).  ACS Applied Materials and Interfaces, 11,9, 8710-8716


Firat-Karalar, E.N. (2019) Cell Scientist to Watch. Journal of Cell Science. 132:jcs238774


Firat-Karalar, E.N., The ciliopathy gene product CEP290 is required for primary cilium formation and microtubule network organization (2018). Turkish Journal of Biology. Volume 42, Issue 5, 371 – 381


Dogru, IB., Min, K., Umar, M., Bahmanin, BJ., Begar, E., Conkar, D., Firat-Karalar, E.N., Kim, S., Nizamoglu, S. (2017). Single transverse mode protein laser. Applied Physics Letters.111 (23), 231103


Dogru, IB., Soz, CD., Press, DA, Melikov, R., Begar, E., Conkar, D., Firat-Karalar, E.N., Yilgor, E., Yilgor, I., Nizamoglu, S. (2017). 3D Coffee Stain. Materials Chemistry Frontiers. August


Conkar, D., Culfa, E., Odabasi, E., Rauniyar, N., Yates, JR 3rd, Firat-Karalar, E.N. The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking (2017). J Cell Sci. Feb 24. jcs.196832.

* Paper selected as cover article, Research Highlight in the FEBS Journal


Press, DA., Rusztamzhon, M., Conkar, D. Firat-Karalar, E.N., Nizamoglu, S. Protein Integrated Solid State Lighting (2016). Nanotechnology Volume 27, Number 45


Publications from graduate and postdoc work

Firat-Karalar, E.N., Sante, J., Elliott, S, Stearns, T. (2014). Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. J Cell Sci. Jul 29. pii: jcs.157008.


Firat-Karalar, E.N., Rauniyar, N., Yates, JR 3rd, Stearns, T. (2014). Proximity interactions among centrosome components identify regulators of centriole duplication. Curr Biol. 24(6): 664-670
* Recommended by Faculty of 1000,


Firat-Karalar, E.N. and Stearns, T. (2014). The Centriole Duplication Cycle. Philos Trans R Soc Lond B Biol Sci. Sep 5; 369(1650). pii:: 20130460.


Firat-Karalar, E.N., Hsiue, P.P., Welch, M.D (2011). The actin nucleation factor JMY is a negative regulator of neuritogenesis. Mol Biol Cell. 22(23): 4563-4574


Firat-Karalar, E.N. and M.D. Welch (2011). New mechanisms and functions of actin nucleation. Curr Opin Cell Biol. 23(1): 4-13


Goley E.D., Rammohan A, Znameroski E.A., Firat-Karalar E.N., Sept D, Welch M.D (2010). An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branching stability. Proc Natl Acad Sci. 107(18): 8159-8164

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