Peer Reviewed Publications (Researchgate, google scholar)

•  I. Goktan, B. E. Günaydın, E. Yalcin, E. Odemis, K. Jalili, S. Kizilel “Deciphering mechanotransduction pathways in cardiomyocytes: In vitro dynamic platform” submitted.
• Syeda R. Batool‡, Isilay Goktan‡, Muhammad A. Nazeer, Burak Erman, Seda Kizilel* “In silico identification of potential Mpro inhibitors for SARS-COV-2” submitted.
• IC Karaoglu, A.O. Kebabcı, S. Kizilel* “Optimization of Gelatin Methacryloyl Hydrogel Properties through an Artificial Neural Network Model” , ACS Applied Materials & Interfaces, https://doi.org/10.1021/acsami.3c12207, Sep 2023.
• M Azar, E. Karaman, B. Beyaz, I. Goktan, A.E. Eyupoglu, S. Kizilel, B. Erman, A. Gul, S. Uysal “Expression and characterization of recombinant IL-1Ra in Aspergillus oryzaeas a system” BMC Biotechnology, volume 23, Article number: 15 (2023).
• S Karaz, G Akay, IC Karaoglu, M Han, S Nizamoglu, S Kizilel*, E Senses* “Shear‐Triggered Release of Lipid Nanoparticles from Tissue‐Mimetic Hydrogels”, Macromolecular Rapid Communications, https://doi.org/10.1002/marc.202300090, 2023, FEATURED AS COVER
• A Kusoglu, K Yangin, et al. “Different Decellularization Methods in Bovine Lung Tissue Reveals Distinct Biochemical Composition, Stiffness and Viscoelasticity in Reconstituted Hydrogels, ACS Appl Bio Mater, 2023 doi: 10.1021/acsabm.2c00968.
• Selcan Karaz, Mertcan Han, Gizem Akay, Asim Onal, Sedat Nizamoglu, Seda Kizilel*, Erkan Senses* “Multiscale Dynamics of Lipid Vesicles in Polymeric Microenvironment” https://doi.org/10.3390/membranes12070640 Membranes 2022, 12(7), 640. 
• Ayesha Gulzar; Erdost Yıldız; Hümeyra Nur Kaleli; Muhammad Anwaar Nazeer; Noushin Zibandeh; Anjum Naeem Malik; Ayşe Yıldız Taş; Ismail Lazoğlu; Afsun Şahin, Seda Kizilel* “Ruthenium-induced Corneal Collagen Crosslinking under Visible Light” Acta Biomaterialia, May 2022.
• Tugba Bal†, Ismail Can Karaoglu†, Fusun Sevval Murat, Esra Yalcin, Yoshihiro Sasaki, Kazunari Akiyoshi, Seda Kizilel* “Immunological response of polysaccharide nanogel-incorporating PEG hydrogels in an in vivo diabetic model“,  Journal of Biomaterials Science, Polymer Edition, May 2022.
• S Darvishi, MA Nazeer, M Tyagi, Q Zhang, S Narayanan, S Kizilel, E Senses Nonlinear Architectures Can Alter the Dynamics of Polymer–Nanoparticle Composites Macromolecules, Oct 2021.
• Nihal O Dogan, Ugur Bozuyuk, Pelin Erkoc, Alp C Karacakol, A Cingoz, F Seker-Polat, M Anwaar Nazeer, Metin Sitti*, Tugba Bagci-Onder*, Seda Kizilel* “Parameters Influencing Gene Delivery Efficiency of PEGylated Chitosan Nanoparticles: Experimental and Modeling Approach“,  Advanced NanoBiomed Research, 2021.
• S. Rubab Batool, M. Anwaar Nazeer, Erdost Yildiz, Afsun Şahin,  Seda Kizilel^* “​Chitosan-Anthracene Hydrogels as Controlled Stiffening Networks”  International Journal of Biological Macromolecules, 2021.
• M. Anwaar Nazeer, İsmail C Karaoglu, Onur Ozer, Cem Albayrak*,  Seda Kizilel^* “​Neovascularization of engineered tissues for clinical translation: where we are, where we should be?” APL Bioengineering (This paper has been selected as Editor’s Pick), Feb 2021.
• M Birgül Akolpoğlu+, Yasemin İnceoğlu+, Ugur Bozuyuk, Ana Rita Sousa^‡, Mariana B. Oliveira^‡*, João F. Mano^‡, Seda Kizilel^†,*  “Recent Advances in the Design of Implantable Insulin Secreting Heterocellular Islet Organoids” Biomaterials (Impact Factor: 10.317), Oct 2020. (+: equal authorship)
• Pelin Erkoc*, Ileyna Uvak, M Anwaar Nazeer, S Rubab Batool, Ozan Akdogan*, Seda Kizilel* “3D Printing of Cytocompatible Gelatin-Cellulose-Alginate Blend Hydrogels” Macromolecular Bioscience, July 2020.
• M Birgül Akolpoğlu+, Nihal O Dogan+, Ugur Bozuyuk+, Hakan Ceylan*, Seda Kizilel*, Metin Sitti* “High-Yield Production of Biohybrid Microalgae for On-Demand Cargo Delivery” Advanced Science (Impact Factor: 15.804), May 2020.
• Syeda Rubab Batool, Muhammad Anwaar Nazeer, Duygu Ekinci, Afsun Sahin, Seda Kizilel* “Multifunctional Alginate-based Hydrogel with Reversible Crosslinking for Controlled Therapeutics Delivery”  International Journal of Biological Macromolecules, https://doi.org/10.1016/j.ijbiomac.2020.02.042, 2020.
• M Birgül Akolpoğlu, Yasemin İnceoğlu, Seda Kizilel* “An All-Aqueous Approach for Physical Immobilization of PEG-lipid Microgels on Organoid Surfaces“, in press, Colloids and Surfaces B: Biointerfaces, 5 December 2019, 110708, 2019.
• T Bal, Y Inceoglu, E Karaoz, Seda Kizilel* “Sensitivity study for the key parameters in Heterospheroid Preparation with Insulin-Secreting β-Cells and Mesenchymal Stem Cells” ACS Biomaterials Science & Engineering, 10.1021/acsbiomaterials.9b00570, Sep 2019.
• Dilem C Oran, M.B. Akolpoglu, Y. Inceoglu, T Lokumcu, O Albayrak, T Bal, M Kurtoğlu, M Erkan, F Can, T Bagci-Onder, Seda Kizilel^{* “}Engineering Human Stellate Cells for Beta Cell Replacement Therapy Promotes in vivo Recruitment of Regulatory T cells (Tregs)” Materials Today Bio, May 2019.
• Betul Bingol, Sesil Agopcan-Cinar, Tugba Bal, D. Ceren Oran, Seda Kizilel, Nilhan Kayaman-Apohan, Duygu Avci* “Stimuli‐responsive Poly(hydroxyethyl methacrylate) Hydrogels from Carboxylic Acid‐Functionalized Crosslinkers” Journal of Biomedical Materials Research Part A, May 2019.
• Ugur Bozuyuk, Ipek Gokulu, Nihal O Dogan, Seda Kizilel* “A Novel Method for PEGylation of Chitosan Nanoparticles through Photopolymerization” RSC Advances, 10.1039/C9RA00780F, 2019.
• C. Kekec, M. B. Akolpoglu, U. Bozuyuk, S. Kizilel, N.Nugay*, T. Nugay, J.P. Kennedy* “Calcification resistance of polyisobutylene and polyisobutylene-based materials”, Polymers for Advanced Technologies, DOI: 10.1002/pat.4616, March 2019.
• Pelin Erkoc, Nihal O. Dogan, Seda Kizilel* “Optimization of Gelatin-Potassium Phosphate Aqueous Two-phase System for the Preparation of Hydrogel Microspheres“ Journal of the Minerals, Metals, and Materials Society (JOMJ), https://doi.org/10.1007/s11837-019-03328-8, 2019. Will appear in the Special Issue on “Protein-Based Structural Materials”
• Ugur Bozuyuk, Nihal Olcay Dogan, Seda Kizilel* “Deep insight into PEGylation of bioadhesive chitosan nanoparticles: Sensitivity analysis for the key parameters through artificial neural network model” ACS Applied Materials & Interfaces, DOI: 10.1021/acsami.8b11178, Sep 2018.
• Ugur Bozuyuk, Oncay Yasa, I Ceren Yasa, Hakan Ceylan*, Seda Kizilel*, Metin Sitti*“Light-Triggered Drug Release from 3D-Printed Magnetic Chitosan Microswimmers” ACS Nano, 10.1021/acsnano.8b05997, August 2018.
• M.N. Guven+ , M.S. Altuncu+, T. Bal , D.C. Oran, U. Gulyuz, S Kizilel, O. Okay, D. Avci* “Bisphosphonic acid functionalized crosslinkers to tailor hydrogel properties for biomedical applications” DOI: 1021/acsomega.8b01103 ACS Omega, 2018.
• Derya Aydin, M. Birgul Akolpoglu, Riza Kizilel, Seda Kizilel* “Anti-Icing Properties on Surfaces through Functional Composite: Effect of Ionic Salts“DOI: 10.1021/acsomega.8b00816 ACS Omega, 2018.
• Tugba Bal, Dilem C Oran, Yoshihiro Sasaki, Kazunari Akiyoshi, Seda Kizilel* “Sequential Coating of Insulin Secreting Beta Cells within Multilayers of Polysaccharide Nanogels” Macromolecular Bioscience, DOI: 10.1002/mabi.201800001, 25 March 2018.
• Derya Aydin, Seda Kizilel* “P2X7 Receptor Antagonist Delivery Vehicle Based on Photocrosslinked Amphiphilic Hybrid Gels” RSC Advances, DOI: 10.1039/c8ra01460d, 2018.
• Pelin Erkoc, Fidan Seker, Tugba Bagci-Onder^*, Seda Kizilel^{* “}Gelatin Methacryloyl Hydrogels in the Absence of a Crosslinker as 3D Glioblastoma Multiforme (GBM)-Mimetic Microenvironment” Macromolecular Bioscience, DOI: 10.1002/mabi.201700369, 2018.
• Sadi Gurses, Can Erkey, Seda Kizilel*, Alper Uzun* “Characterization of Sodium Tripolyphosphate and Sodium Citrate Dehydrate Residues on Surfaces” Talanta, Vol 176, pp 8-16 August 2017.
• Gunce E Cinay, Pelin Erkoc, Mohammad Alipour, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Seda Kizilel* “Nanogel-integrated pH Responsive Composite Hydrogels for Controlled Drug Delivery” ACS Biomaterials Science & Engineering DOI: 10.1021/acsbiomaterials.6b00670, Jan 2017.
• Pelin Erkoc, Ahmet Cingoz, Tugba Bagci-Onder*, Seda Kizilel* “Quinacrine Mediated Sensitization of Glioblastoma (GBM) cells to TRAIL through MMP-sensitive PEG Hydrogel Carriers” Macromolecular Bioscience, DOI: 10.1002/mabi.201600267, Vol 17, Issue 2, 20 October 2016.
• FEATURED as Frontispiece in  this issue of Macromolecular Bioscience.
• Aysu C Okur+, Pelin Erkoc+, Seda Kizilel* “Targeting Cancer Cells via Tumor-homing Peptide CREKA Functional PEG Hydrogel Nanoparticles” Colloids and Surfaces B: Biointerfaces, 10.1016/j.colsurfb.2016.08.005, August 2016.
• Derya Aydin, Seda Kizilel* “Water-in-Water Emulsion Based Synthesis of Hydrogel Nanospheres with Tunable Release Kinetics” Journal of the Minerals, Metals, and Materials Society (JOMJ), DOI: 10.1007/s11837-016-1969-z, 2016.
•  INVITED – Special Issue on “Biomaterials for Healthcare”
• Derya Aydin, Riza Kizilel, Ramazan O Caniaz, Seda Kizilel* “Gelation Stabilized Functional Composite-Modified Bitumen for Anti-icing Purposes” DOI: 10.1021/acs.iecr.5b03028, Industrial and Engineering Chemistry Research, Nov 2015.
• This article in I&ECR has been selected as the topic of a press release that is included in the American Chemical Society (ACS) Office of Public Affairs’ weekly presspac.
• Here are some of the news about our work:  Sciencedaily, Science Newsline, NTV, TGRT, HALKTV, KANAL 24
• Dogan Gidon⁺, Derya Aydin⁺, Seda Kizilel* “Photocrosslinking of Styrene-Butadiene-Styrene (SBS) Networks formed by Thiol-Ene Reactions and Their Influence on Cell Survival” doi:10.1088/1748-6041/10/6/065001, Biomedical Materials, October 2015 (⁺:equal authorship).
• Gozde S Demirer, Aysu C Okur, Seda Kizilel* “Biologically Inspired Design of Biocompatible Iron Oxide Nanoparticles for Biomedical Applications” Journal of Materials Chemistry B, DOI: 10.1039/c5tb00931f, July 2015.
• INVITED – Special Issue on “Bioinspired and Natural Materials” 
• H. Betul Bingol, Ayse Altin, Tugba Bal, Sesil Agopcan-Cinar, Seda Kizilel, Duygu Avci* “Synthesis and evaluation of new phosphonic acid-functionalized acrylamides with potential biomedical applications“Journal of Polymer Science Part A,  DOI: 10.1002/pola.27746, 2015.
• Ozlem Cevik, Dogan Gidon, Seda Kizilel* “Visible-Light-Induced Synthesis of pH Responsive Hydrogel Composite for Controlled Delivery of an Anticonvulsant Drug Pregabalin” in press, Acta Biomaterialia,10.1016/j.actbio.2014.09.018, January 2015.
• Tugba Bal, Caner Nazli, Alparslan Okcu, Gokhan Duruksu, Erdal Karaoz, Seda Kizilel^{* “}Mesenchymal Stem Cells (MSCs) and Ligand Incorporation in Biomimetic PEG Hydrogels Significantly Improve Insulin Secretion from Pancreatic Islets” Journal of Tissue Engineering and Regenerative Medicine, DOI:10.1002/term.1965, 2014.
• Caner Nazli, Gozde S Demirer, Y Yar, H. Yagci Acar, Seda Kizilel* “Targeted Delivery of Doxorubicin into Tumor Cells via MMP-sensitive PEG Hydrogel Coated Magnetic Iron Oxide Nanoparticles (MIONPs)“, Colloids and Surfaces B: Biointerfaces, 10.1016/j.colsurfb.2014.07.049, 2014.
• Burcu Kepsutlu, Caner Nazli, Tugba Bal, Seda Kizilel* “Design of Bioartificial Pancreas with Functional Micro/Nano Based Encapsulation of Islets” Current Pharmaceutical Biotechnology, 15(7), 590-608, 2014. DOI: 10.2174/1389201015666140915145709
• INVITED – Special Thematic Issue on “Nanotechnology as a Strategy to Improve Treatment of Diabetes”
• K Golab, S Kizilel, T Bal, M Hara, M Zielinski, R Grose, O Savari, XJ Wang, J Grzanka, L-J Wang, M Tibudan, A Krzystyniak, N Marek-Trzonkowska, JM Millis, P Trzonkowski, P Witkowski “Improved Coating of Pancreatic Islets with Regulatory T cells (Tregs) to Create Local Immunosuppression by Using Biotin-Polyethylene glycol-Succinimidyl Valeric Acid Ester Molecule.” Transplantation Proceedings Volume 46, Issue 6, July-August 2014, Pages 1967-1971, DOI: 10.1016/j.transproceed.2014.05.075.
• Burcu Kepsutlu, Riza Kizilel, Seda Kizilel* “Quantification of Interactions Among Circadian Clock Proteins via SPR” Journal of Molecular Recognition, DOI: 10.1002/jmr.2367,  2014.
• Selin Kanyas, Derya Aydin, Riza Kizilel, A. Levent Demirel, Seda Kizilel*, “Nanoparticle and Gelation Stabilized Functional Composites of an Ionic Salt in a Hydrophobic Polymer Matrix”  PLoS ONE, DOI: 10.1371/journal.pone.0088125, 2014.
• Tugba Bal, Burcu Kepsutlu, Seda Kizilel*, “Characterization of Protein Release through PEG Hydrogels with Crosslink Density Gradients” DOI: 10.1002/jbm.a.34701, Journal of Biomedical Materials Research Part A, March 2013.
• Selimcan Azizoglu, Riza Kizilel, Maja Marusic, I. Halil Kavakli, Burak Erman, Seda Kizilel,* “Computational and Experimental Investigation of Drug-Protein Interactions” Journal of Molecular Recognition, DOI: 10.1002/jmr.2258, 26: 297-307, 2013.
• Riza Kizilel,* Enis Demir, Selimcan Azizoglu, Hande Asimgil, I. Halil Kavakli,* Seda Kizilel,* “Investigation of Real-Time Photorepair Activity on DNA via Surface Plasmon Resonance (SPR)” PLoS ONE, 7(8): e44392. doi:10.1371/journal.pone.0044392, 2012.
• Caner Nazli, T. Ipek Ergenc, Yasemin Yar, Funda Yagci Acar, Seda Kizilel* “RGDS Functionalized Poly(ethylene glycol) (PEG) Hydrogel Coated Magnetic Iron Oxide Nanoparticles Enhance Specific Intracellular Uptake by HeLa Cells” International Journal of Nanomedicine, 7:1903-1920, 2012.
• Bilal Cakir, Onur Dagliyan, Ezgi Dagyildiz, Ibrahim Baris, I. Halil Kavakli*, Seda Kizilel*, Metin Turkay* “Structure Based Discovery of Small Molecules to Regulate the Activity of Insulin Degrading Enzyme” PLoS ONE, 7(2): e31787, DOI: 10.1371/journal.pone.0031787, 2012.
• Riza Kizilel, Seda Kizilel* “Application of Numerical Fractionation Approach for the Design of Biofunctional PEG Hydrogel Membrane” Macromolecular Reaction Engineering, March 13, DOI:10.1002/mren.201100073, 2012 (APPEARED AS COVER).(pdf)
• Seda Giray, Tugba Bal, Ayse Meric Kartal, Seda Kizilel,* and Can Erkey* “Controlled Drug Delivery through a Novel PEG Hydrogel Encapsulated Silica Aerogel System” Journal of Biomedical Materials Research Part A, DOI: 10.1002/jbm.a.34056, 2012.
• Natalia Marek+, Adam Krzystyniak+, T. Ipek Ergenc+, Olivia Cochet, Ryosuke Misawa, Ling-Jia Wang, Seda Kizilel, Piotr Trzonkowski, Michael Millis, Piotr Witkowski “Coating of Human Pancreatic Islets with CD4+CD25highCD127-T Regulatory Cells-a Novel Immunosuppressive Approach” Annals of Surgery, Volume 254, Number 3, September 2011 (+ = equal authorship). (pdf)
• Seda Keskin and Seda Kizilel “Biomedical Applications of Metal Organic Frameworks” Industrial and Engineering Chemistry Research, 50(4), 1799-1812, 2011.
•  Seda Kizilel* “Mathematical Model for Microencapsulation of Pancreatic Islets within Biofunctional PEG Hydrogel” , Macromolecular Theory and Simulations, 2010, 19(8-9):514-531. (pdf)
• Seda Kizilel*, Andrew Scavone, Xiang Liu, Jean Manuel Nothias, Diane Ostrega, Piotr Witkowski, J Michael Millis “Encapsulation of Pancreatic Islets Within Nano-Thin Functional Polyethylene Glycol Coatings for Enhanced Insulin Secretion.” Tissue Engineering Part A, 2010, 16(7):2217-28. (pdf)
• Seda Kizilel*, Fouad Teymour, and Victor H. Perez-Luna “Modeling of PEG Hydrogel Membrane for Biomedical Applications“, Macromolecular Reaction Engineering, 2009, 3:271-287.(pdf)
• Seda Kizilel, Georgia Papavasiliou, John Gossage, Fouad Teymour* “Mathematical Model for Vinyl-Divinyl Polymerization” Macromolecular Reaction Engineering, 2007, 1: 587-603.(pdf)
•  J.L. Wyman, S. Kizilel, R. Skarbek, X. Zhao, M. Connors, W.S. Dillmore, W.L. Murphy, M. Mrksich, S.R. Nagel, M.R. Garfinkel. Immunoisolating pancreatic islets by encapsulation with selective withdrawal. Small, 2007, 3:683-690.
• Seda Kizilel, Erin Sawardecker, Victor H. Perez-Luna*, and Fouad Teymour, “Sequential Formation of Covalently Bonded Hydrogel Multilayers through Surface Initiated Photopolymerization” Biomaterials, 2006; 27(8):1209-1215.(pdf)
• Seda Kizilel*, Fouad Teymour, and Victor H. Perez-Luna “Mathematical Model for Surface Initiated Photopolymerization of Poly(ethylene glycol) Diacrylate” Macromolecular Theory and Simulations, 2006; 15(9):686-700.(pdf)
• Seda Kizilel, Marc Garfinkel, Emmanuel Opara* “The Bioartificial Pancreas: Progress and Challenges” Diabetes Technology and Therapeutics, 2005; 7(6):968-985.
• Seda Kizilel, Victor H. Perez-Luna*, and Fouad Teymour “Photopolymerization of poly(ethylene glycol) diacrylate on eosin-functionalized surfaces” Langmuir , 2004; 20(20); 8652-8658.(pdf)