CHBI 502


Syllabus, Spring  2016


Course Description:             Design and operation of chemical reactors. Homogeneous, heterogeneous and biochemical reactions. Ideal and non-ideal reactors. Kinetics of enzyme-catalyzed reactions. Kinetics of substrate utilization and biomass production.                                                Prerequisite: Consent of the instructor

Instructor:                              Özlem Keskin

Office:                                    Eng 224 

Office Hours                         Anytime

Textbook                                Elements of Chemical Reaction Engineering (4th ed.), H.S. Fogler Prentice Hall, Upper Saddle River, NJ (2005).

Class Hours                           Mon 16:15 Wed 16:15

Place                                       CASEB26


Attendance                            In accordance with University policy, students are expected to attend all lectures. Regular attendance and participation in class and problem sessions will be taken into positive consideration in determining the grades of all students.


Grading                                  Midterm                                               30%

Final                                                    35%

Homeworks                                         20%

Project                                                 15%




Academic dishonesty in the form of cheating, plagiarism and collusion are serious offenses and will not be tolerated at Koc University. University Academic Regulations and the Regulations for Student Disciplinary Matters clearly define the policy and the disciplinary action to be taken in case of academic dishonesty. However, if proven guilty, usually the toughest punishment is given to the student, especially if (s)he tries to mislead the commission by lying to them.


Cheating includes, but is not limited to, copying from a classmate or providing answers or information, either written or oral to others. Plagiarism is borrowing or using someone else’s writing or ideas without giving written acknowledgement to the author. This includes copying from a fellow student’s paper or from a text without properly citing the source. Collusion is getting unauthorized help from another person or having someone else write one’s paper or assignment.


Course Outline

Tentative schedule



Chapter 1:       Mole Balances (0.5 week)

Chapter 2:       Conversion and Reactor Sizing (0.5week)

Chapter 3:       Rate Law and Stoichiometry

Collision theory (1 week)

Transition State Theory (1 week)

Chapter 4:       Isothermal Reactor Design (0.5week)

Chapter 5:       Collection and Analysis of Rate Data (0.5 week)

Chapter 6:       Multiple Reactions (0.5 week)


1,5 weeks

Chapter 7:       Reaction Mechanisms, Pathways, Bioreactions and Bioreactors


One week

Chapter 8:       Steady-State Nonisothermal Reactor Design


One week

Chapter 9:       Unsteady-state Nonisothermal Reactor Design


Two weeks

Chapter 10:     Catalysis and Catalytic Reactors

Kinetics of enzyme-catalyzed reactions

Kinetics of substrate utilization and biomass production


One Week

Chapter 11: External Diffusion Effects on Heterogeneous Reactions


Two Weeks

Chapter 12: Diffusion and Reaction in Porous Catalysts


Two weeks

Student presentations on projects